{"id":90,"date":"2018-10-24T11:37:23","date_gmt":"2018-10-24T11:37:23","guid":{"rendered":"http:\/\/psyc.bbk.ac.uk\/gel\/?page_id=90"},"modified":"2024-06-18T11:10:26","modified_gmt":"2024-06-18T10:10:26","slug":"the-leap-project","status":"publish","type":"page","link":"https:\/\/psyc.bbk.ac.uk\/gel\/research\/the-leap-project\/","title":{"rendered":"The LEAP Project"},"content":{"rendered":"<p><strong>GEL team members working on the project<\/strong>: <a href=\"http:\/\/www.gel.bbk.ac.uk\/about-us\/professor-angelica-ronald-lab-director\/\" target=\"_blank\" rel=\"noopener noreferrer\">Professor Angelica Ronald<\/a>, <a href=\"http:\/\/www.gel.bbk.ac.uk\/about-us\/laura-havers-13-phd-student\/\" target=\"_blank\" rel=\"noopener noreferrer\">Laura Havers<\/a><\/p>\n<p><strong>Collaborators include: <\/strong><a href=\"https:\/\/www.psych.ox.ac.uk\/team\/daniel-freeman\" target=\"_blank\" rel=\"noopener noreferrer\">Prof Daniel Freeman<\/a>, <a href=\"https:\/\/kclpure.kcl.ac.uk\/portal\/robert.plomin.html\" target=\"_blank\" rel=\"noopener noreferrer\">Prof Robert Plomin,<\/a>\u00a0<a href=\"https:\/\/kclpure.kcl.ac.uk\/portal\/philip.mcguire.html\" target=\"_blank\" rel=\"noopener noreferrer\">Professor Philip McGuire<\/a><\/p>\n<p><strong>Funded by:<\/strong> The Medical Research Council and Wellcome Trust ISSF award<\/p>\n<p><strong>The Project: <\/strong>This Medical Research Council-funded project aims to characterise the aetiology of psychotic experiences in adolescence. It is hoped that by understanding the causes of psychotic experiences in 15- to 18-year-olds this knowledge can inform the development of early interventions<\/p>\n<p><strong>Publications<\/strong><\/p>\n<p><span lang=\"EN-US\">Barkhuizen, W., Taylor, M. J., Freeman, D. and Ronald, A. <\/span><span lang=\"EN-US\">(2019). A twin study on the association between psychotic experiences and tobacco use during adolescence<\/span><em><span lang=\"EN-US\">. Journal of the American Academy of Child and Adolescent Psychiatry, <\/span><span lang=\"EN-US\">58,<\/span> <\/em><span lang=\"EN-US\">267-276<\/span><\/p>\n<p>Ronald, A.\u00a0&amp; Pain, O. (2018). A systematic review of genome-wide research on psychotic experiences and negative symptom traits: New revelations and their implications for psychiatry.\u00a0<em>Human Molecular Genetics,\u00a0<\/em><em>1;27(R2),<\/em> R136-R152<\/p>\n<p>Shakoor, S., McGuire, P., Cardno, A. G., Freeman, D. &amp;\u00a0Ronald, A.\u00a0(2018). A twin study exploring the association between childhood emotional and behaviour problems and specific psychotic experiences in a community sample of adolescents.\u00a0<em>Journal of Child Psychology &amp; Psychiatry, 59,\u00a0<\/em>565-573.<\/p>\n<p>Pain, O., Dudbridge, F., Cardno, A.G., Freeman, D., Yi, L., Lundstrom, S., Lichtenstein, P. &amp; Ronald, A. (2018). Genome-wide analysis of adolescent psychotic-like experiences shows genetic overlap with psychiatric disorders. <em>Neuropsychiatric Genetics, 177, <\/em>416-425<em>.<\/em><\/p>\n<p>Cheesman, R., Selzam, S., Ronald, A., Dale, P. S., McAdams, T. A., Eley, T. C. &amp; Plomin, R. (2017). Childhood behaviour problems show the greatest gap between DNA-based and twin heritability. <em>Translational Psychiatry, <\/em>7(12):1284.<\/p>\n<p>Hosang, G., Cardno, A.G., Freeman, D., &amp; Ronald, A. (2017). Characterization and structure of hypomania in a British nonclinical adolescent sample. <em>Journal of Affective Disorders, 207,<\/em> 228-235<em>. <\/em><\/p>\n<p>Singham, T., Viding, E., Schoeler, T., Arseneault, L., Ronald, A., Cecil, C. M., McCrory, E., Rijsdijk, F., Pingault, J. (2017). Concurrent and longitudinal impact of peer victimisation on mental health: A tale of vulnerability and resilience. <em>JAMA Psychiatry, 74,<\/em> 1112-1119.<\/p>\n<p>Shakoor, S., Zavos, H., Haworth, C. M. A., McGuire, P., Cardno, A. G., Freeman, D., &amp; Ronald, A. (2016). Association between stressful life events and psychotic experiences in adolescence: evidence for gene-environment correlations<em>. British Journal of Psychiatry, <\/em><em>208<\/em>, 532-8<em>.<\/em><\/p>\n<p>Taylor, M. J., Freeman, D. &amp; Ronald, A. (2016). Dimensional psychotic experiences in adolescence: Evidence from a taxometric study of a community-based sample. <em>Psychiatry Research, 241<\/em>, 35-42.<\/p>\n<p>Zavos, H. M. S., Eley, T. C., McGuire, P., Plomin, R., Cardno, A. G., Freeman. D. &amp; Ronald, A. (2016). Shared etiology of psychotic experiences and depressive symptoms in adolescence: A longitudinal twin study. <em>Schizophrenia Bulletin, <\/em><em>42,<\/em> 1197-206<em>.<\/em><\/p>\n<p>Shakoor, S., McGuire, P., Cardno, A. G., Freeman, D., Plomin, R., &amp;\u00a0Ronald, A. (2015). A shared genetic propensity underlies experiences of bullying victimization in late childhood and self-rated paranoid thinking in adolescence. <em>Schizophrenia Bulletin, 41,<\/em> 754-63<em>.<\/em><em>\u2028<\/em><\/p>\n<p>Shakoor, S., Zavos, H. M. S., McGuire, P., Cardno, A. G., Freeman, D., &amp; Ronald, A. (2015). Psychotic experiences are linked to cannabis use in adolescents in the community because of common underlying environmental risk factors. <em>Psychiatry Research, 227<\/em>, 144-151<em>.<\/em><\/p>\n<p>Sieradzka, D., Power, R. A., Freeman, D., Cardno, A. G., Dudbridge, F., &amp; Ronald, A. (2015). Heritability of individual psychotic experiences captured by common genetic variants in a community sample of adolescents. <em>Behavior Genetics, 45, <\/em>493-502<em>.<\/em><\/p>\n<p>Taylor, M. J., Gregory, A. M., Freeman, D. &amp; Ronald, A. (2015). Do sleep disturbances and psychotic-like experiences in adolescence share genetic and environmental influences? <em>Journal of Abnormal Psychology, 124,<\/em> 674-84.<\/p>\n<p>Taylor, M.J., Robinson, E.B., Happ\u00e9, F., Bolton, P., Freeman, D., &amp; Ronald, A. (2015). A longitudinal\u00a0twin study of the association between childhood autistic traits and psychotic experiences in adolescence. <em>Molecular Autism, <\/em><em>6,<\/em> 44<em>.\u00a0 <\/em><\/p>\n<p>Ronald A, Sieradzka D, Cardno A. G., Haworth C. M. A, McGuire P, &amp; Freeman D. (2014). Characterization of psychotic experiences in adolescence using the Specific Psychotic Experiences Questionnaire (SPEQ): Findings from a study of 5000 16-year-old twins. <em>Schizophrenia Bulletin, <\/em>40, 868-77.<\/p>\n<p>Sieradzka, D., Power, R.A., Freeman, D., Cardno, A.D., McGuire, P., Plomin, R, Meaburn, E. L., Dudbridge, F., &amp; Ronald A. (2014). Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence? <em>PlosOne <\/em>9(4):e94398. doi: 10.1371\/journal.pone.0094398.<\/p>\n<p>Zavos, H.M.S., Freeman, D., Haworth, C.M.A., McGuire, P., Plomin, R., Cardno, A.G., &amp; Ronald, A. (2014). Consistent etiology of severe, frequent psychotic experiences and milder, less frequent manifestations: A twin study of specific psychotic experiences in adolescence. <em>JAMA Psychiatry, 71<\/em>, 1049-1057.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>GEL team members working on the project: Professor Angelica Ronald, Laura Havers Collaborators include: Prof Daniel Freeman, Prof Robert Plomin,\u00a0Professor Philip McGuire Funded by: The Medical Research Council and Wellcome Trust ISSF award The Project: This Medical Research Council-funded project aims to characterise the aetiology of psychotic experiences in adolescence. It is hoped that by [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":16,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-with-sidebar","meta":{"_crdt_document":"","_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-90","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/psyc.bbk.ac.uk\/gel\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"GEL team members working on the project: Professor Angelica Ronald, Laura Havers Collaborators include: Prof Daniel Freeman, Prof Robert Plomin,\u00a0Professor Philip McGuire Funded by: The Medical Research Council and Wellcome Trust ISSF award The Project: This Medical Research Council-funded project aims to characterise the aetiology of psychotic experiences in adolescence. It is hoped that by&hellip;","_links":{"self":[{"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/pages\/90","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/comments?post=90"}],"version-history":[{"count":1,"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/pages\/90\/revisions"}],"predecessor-version":[{"id":1183,"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/pages\/90\/revisions\/1183"}],"up":[{"embeddable":true,"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/pages\/16"}],"wp:attachment":[{"href":"https:\/\/psyc.bbk.ac.uk\/gel\/wp-json\/wp\/v2\/media?parent=90"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}